He faced revoltsin the Deccan and Bundelkhand by Jujhar Singh, the son of Bir Singh Bundela.
He was married to the daughter of Asaf Khan named Arjumand Bano Begum,also known as Mumtaz Mahal.
He built the TajMahal in Agra and the Jama Masjid (sand stone) in Delhi.
Ustad Isa was the master architect under whose guidance the TajMahal was designed and constructed in Agra.
He built the Red Fort and Taqt-i-Taus (Peacock Throne) in Shahjahanabad.